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Reviewing various treatment plans, the progress and velocity of intravenous infusion must be strictly controlled. Undeniable, present artificial monitoring methods not only increase the burden of patients, relatives and medical staff, but are vulnerable to lead oversight as well. This paper presents the design and implementation of a novel wireless sensor network for intravenous infusion monitoring based on slot-coupled infrared emitting diode as sensors, chip ATMEGE128L as MCU and chip CC2420 as ZigBee-based RF communication. The system has following characteristics: non-touch droplet monitor, easy to reuse, multiple protections on system accuracy and reliability, easy to integrate with existing hospital management system due to flexible design of the host computer software, low cost, and easy to launch large-scale applications.