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Open-access phototransistor-based optoelectronic tweezers for long-term single cell heterogeneity study

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7 Author(s)
Hsu, H.Y. ; Electr. Eng. & Comput. Sci., Univ. of California, Berkeley, CA, USA ; Jamshidi, A. ; Shekarchian, S. ; Lam, W.
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We demonstrate, for the first-time, long-term culturing of single cells under continuous phototransistor-based optoelectronic tweezers (Ph-OET) trapping. A new device configuration, open-access Ph-OET, is presented to integrate the trapping functionality of Ph-OET with culturing capabilities in a Petri dish. Maintenance of human leukemia cell lines (K562, Jurkat) under optical manipulation for up to five cell generation has been achieved.

Published in:

Micro Electro Mechanical Systems (MEMS), 2011 IEEE 24th International Conference on

Date of Conference:

23-27 Jan. 2011