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Proton Exchange Membrane fuel cell (PEMFC) is one of the promising technologies for the distributed power generation. For designing high efficiency fuel cell power systems, a suitable DC-DC converter is required. Among the various topologies, interleaved boost converter (IBC) is considered as a better solution for fuel cell systems, due to improved electrical performance, reduced weight and size. Detailed analysis has been done to investigate the benefits of interleaved boost converter compared to the conventional boost converter. In this paper, the electrochemical modeling of a Proton Exchange Membrane Fuel Cell (PEMFC) has been carried out. A two phase interleaved boost converter is suggested for fuel cells, considering variation of input voltage, inductance and switching frequency. Simulation study for the IBC interfaced with fuel cells has been studied using MATLAB/SIMULEVK.