Referenced Items are not available for this document.
This work presents a multi-component chip that: (i) traps settling cells into poly(dimethyl siloxane) microwells; and (ii) senses the binding of antibodies to antigen immobilized onto a gold surface via the surface plasmon resonance shifts of milled nanohole arrays. We have previously detected the 17/9 antibodies secreted by ~200 hybridoma cells/trap. This work demonstrates our system's current capabilities and limitations via a follow-up experiment using a reduced ~5-20 hybridoma cells/trap density.
Published in:
Sensors, 2010 IEEE
Date of Conference: 1-4 Nov. 2010
- Page(s):
- 2105 - 2108
- ISSN :
- 1930-0395
- E-ISBN :
- 978-1-4244-8168-2
- Print ISBN:
- 978-1-4244-8170-5
- INSPEC Accession Number:
- 11831465
- Conference Location :
- Kona, HI
- Digital Object Identifier :
- 10.1109/ICSENS.2010.5690366
- Product Type:
- Conference Publications
About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies
A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2013 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.
