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This paper presents an architecture for home telemonitoring scenarios based on ontology model solution. It can be divided into physical and conceptual layer. In the conceptual layer, the ontology is used as a common knowledge representation of involved data in the telemonitoring process. In this way, a formal solution to integrate information in both end sites of a telemonitoring scenario and also to the communication between them is provided. In the physical layer, the communication between the main sites of the architecture is done through ontology instances exchange using web service technologies. The main modules developed in the architecture and their functionality are also reported. Finally, a communication data flow example between the units of the architecture for a generic patient telemonitoring process is presented.