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Computational simulation of blood flow dynamics using an anatomically realistic artery model constructed from medical images

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3 Author(s)
Shimogonya, Y. ; Grad. Sch. of Eng., Univ. of Hyogo, Himeji, Japan ; Itoh, K. ; Kumamaru, H.

Hemodynamics is believed to play a vital role in the initiation of cerebral aneurysms. In this study, we describe a newly defined hemodynamic quantity, the gradient oscillatory number (GON), as an index for the cerebral aneurysm initiation. It is defined by temporal variations of flow-induced tension/compression forces acting on endothelial cells. We calculated the index for the arterial geometry before aneurysm formation, which was constructed by artificially removing the aneurysm from a medical image-based arterial geometry. The result showed that the index had a strong correlation with the location of aneurysm formation. This suggests that the proposed index, GON, may be useful as a hemodynamic index for the initiation of cerebral aneurysms.

Published in:

World Automation Congress (WAC), 2010

Date of Conference:

19-23 Sept. 2010

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