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Ni-12at.%V alloy is a promising candidate for non-magnetic cube textured metallic substrates used for high temperature coated conductors. In this work, a textured Ni-12at.%V substrate has been fabricated by powder metallurgy route. After cold rolling and recrystallization annealing, a cube texture content as high as 99% (<;10°) was obtained, and the low angle grain boundary fraction is 89%. In addition, the FWHM values of phi-scan and rocking curve are 7.77° and 7.37°, respectively. According to micro-hardness measurement, the HV value of Ni-12at.%V tape is three times higher than that of pure Ni and to a certain extent higher than that of Ni-5at.%W. Furthermore, the Curie temperature of the Ni-12at.%V substrate is decreased to less than 77 K due to the addition of vanadium element in Ni.