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Emerging multi-core platforms are increasingly impacted by the manufacturing process variations that introduce core-to-core and chip-to-chip differences in their power and performance characteristics. This can result in unacceptable yield loss since a large fraction of manufactured parts may not meet the design specifications. In this work, we present some promising, recently proposed solutions to mitigate the impact of process variations on multi-core platforms that deal with variability aware performance modeling, and static and dynamic power reduction. These solutions demonstrate the significant benefits that can be reaped if variability information is considered at the micro-architecture and system level design abstractions.