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In this paper, a miniature low-power Electrocardiogram (ECG) signal processing application specific integrated circuit (ASIC) chip is proposed. This chip provides multiple critical functions for ECG analysis using a systematic wavelet transform algorithm and a novel SRAM-based ASIC architecture, while achieves low cost and high performance. Using 0.18 μm CMOS technology and 1 V power supply, this ASIC chip consumes only 29 μW and occupies an area of 3 mm2. This on-chip ECG processor is highly suitable for reliable real-time cardiac status monitoring applications.