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Medical image understanding is a computing process of object recognition in medical image using computer vision, applied mathematics, signal analysis and artificial intelligence. This paper provides a medical image understanding process definition language (MPDL) which aims at solving the problem of object recognition in medical image and satisfying the requisition of stable and high precision medical image analysis software engineering. MPDL supports coding, debugging, maintenance and share of medical image understanding algorithm. A software component model of medical image understanding algorithm and a mechanism of mapping and synchronization between component and process node in medical image understanding process are represented. The method of validating a medical image understanding process definition is showed in addition. The rationality and applicability of this language is validated by a platform of medical image understanding algorithm development which uses MPDL.