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An early detection of small breast lesions by mammography screening may facilitate the cancer treatment by minimally or noninvasive techniques. Recently, new therapies than traditional surgery have been explored to satisfy these demands. Additionally ablative treatments have started to become viable alternative methods to treat patients who cannot be treated by surgery. Microwave energy is promising because it can preferentially heat and damage high-water-content breast carcinomas, compared with the lesser degrees of heating that occurs in lower-water-content adipose and breast glandular tissues. Furthermore the relatively high contrast between the electrical property of normal and cancerous tissues leads to preferential deposition of electromagnetic energy and selective thermal elevation within the tumor. The aim of this work was to analyze the Microwave Ablation radius lesion using an axisymmetric finite element method computer modeling with an experimental ablation in ex vivo swine adipose-dominated breast tissue. Our results show that advanced computer modeling and ex vivo experiments agree very good.