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In this paper, some recent results obtained with film-type sensor materials polyvinylidenefluoride (PVDF) and electromechanical film (EMFi) are presented. The materials generate a voltage when they are mechanically deformed, however, because of their capacitive nature only the change of an external force can be measured. Hence, the sensors made of these materials are useful especially in the measurements of physiological pulsatile signals (e.g., heart rate and respiration). The entire measurement process with the PVDF and EMFi sensors is considered here; from the design and construction of the sensors and measurement electronics to the analysis of the measured data. The paper also presents some examples of the physiological signals (heart rate, respiration, and heart sounds) measured with the PVDF and EMFi sensors. Flexible and thin sensor materials are useful especially in physiological applications where the sensor is integrated into clothing or into daily life objects (e.g., a chair or a bed). The sensor attachments to human can be minimized and the measurement systems can be designed to be unobtrusive and comfortable for the user.