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This paper discusses the use of Abrasive Water Suspension Jets (AWSJ) for the cutting of glass. The experimental investigation of the combined effect of process parameters on the depth of cut and kerf width produced by AWSJ has been carried out using Design of Experiments (DOE). DOE tools such as Orthogonal Array (OA) and Analysis of Variance (ANOVA) have been used to design the experiments and to analyze the experimental data respectively. ANOVA results indicate that the effect of pressure on depth of cut is maximum (50%) followed by abrasive size (22%) and feed (12%). Whereas the effect of standoff distance on kerf width is maximum (75%) followed by pressure (17%).