By Topic

GPTS functionalized carbon nanotubes integrated with PZT sensors for detection of anti-goat IgG

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

4 Author(s)
Ting Xu ; Sch. of Mech. & Aerosp. Eng., Nanyang Technol. Univ., Singapore, Singapore ; Jianmin Miao ; Liu, Y. ; Li, C.M.

In this paper, we present a new method of using functionalized multi-walled carbon nanotubes (MWCNTs) to specifically detect anti-goat IgG. 3-Glycidoxypropyl-trimethoxysilane (GPTS) was immobilized onto the CNT surface to introduce epoxy ring and goat IgG was used as a biological probe. Afterwards, blockers were used to occupy the open space in the CNT surface, and finally anti-goat IgGs were detected by the functionalized MWCNTs. FSEM, AFM, TEM, and AT-FIR were used to characterize the physical and chemical property changes during each process. AFM results showed the CNT diameters increased accordingly as more immobilization processes were conducted. AT-FIR spectrum confirmed the success of biomolecules binding with CNTs in each process. The functionalized CNT for anti-goat IgG sensing was verified by another piezoelectric sensor. The functionalized MWCNTs could then be potentially used for immunosensor or incorporated with other sensors to enhance the sensitivity.

Published in:

Nano/Micro Engineered and Molecular Systems (NEMS), 2010 5th IEEE International Conference on

Date of Conference:

20-23 Jan. 2010