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For transmission of multimedia over 3G wireless networks, H.264/AVC represents a major step forward in the development of video coding standards. In this paper, firstly, the authors briefly introduce a overview of H.264/AVC standard and propose the related coding tools, usingDM6446. Then, the paper gives the hardware and software design of a simulation system, this system can acquire the multimedia information and send the information by 3G interface. At the last section, the authors compare the H.264/AVC standard with other prior coding standards. The results show that H.264/AVC standard will enable new applications and business opportunities to be developed.