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Single-Ion Channel Recordings on Quartz Substrates

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4 Author(s)
Stava, E. ; Dept. of Electr. & Comput. Eng., Univ. of Wisconsin-Madison, Madison, WI, USA ; Yu, Minrui ; Hyun Cheol Shin ; Blick, Robert H.

We show that a single-crystal quartz substrate provides a working platform for ion channel research. Single-crystal quartz is piezoelectric, so it can be nanomechanically actuated to perform precise membrane deformations. This, along with its superior noise properties, makes single-crystal quartz ideal for analyzing mechanosensitive ion channels.

Published in:

NanoBioscience, IEEE Transactions on  (Volume:9 ,  Issue: 4 )