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This paper first introduced the development of a urban earthquake disaster management information system (UEDMIS), including the system framework, earthquake and infrastructure related database, disaster estimation and decision optimization models, functions of the software and sample interface of the software. Other than the earthquake disaster information management, the UEDMIS also can be used for emergency response for earthquake and other similar disaster incidents. How can the UEDMIS be used for incidents response? This paper gives some advices and envisages secondly.