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It is a challenging task to analyze dynamic performance of a practical supply network system, as well as performance of its members. This paper addresses this problem, and proposes a new framework for multi-agent approach. In the paper, the primary objects required for supply network simulations are defined. The static relationships among these objects and dynamic order in which they interact with each other are also presented. Finally, a simple four-echelon supply network system is simulated to validate and illustrate the framework.