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During the construction of scientific and technical resources database system two problems are urgent to be solved. The first is how to fully protect existing investment, realize the resource integration, and reduce the construction cost. The second is how to respond to the change of the business needs rapidly, constantly meet applications. It is difficult to solve these two problems with existing mature technology. Service oriented architecture (SOA) offers a solution to the software reuse in distributed environment, and expands and improves the efficiency of software development. By using the SOA principle, the paper realizes the modeling and development of scientific and technical resources database system. The practice has proved that the system has better flexibility and maintainability.