Scheduled System Maintenance:
Some services will be unavailable Sunday, March 29th through Monday, March 30th. We apologize for the inconvenience.
By Topic

Selective Detection of Chemical and Biological Toxins Using Gold-Nanoparticle-Based Two-Photon Scattering Assay

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

15 Author(s)
Neeley, A. ; Jackson State Univ., Jackson, MS, USA ; Khan, S.A. ; Beqa, L. ; Zhen Fan
more authors

Possible terrorist threats on water supplies are causes for concern given the easy availability of numerous biological and chemical toxins that could be used by a terrorist organization. In this article, we report gold-nanoparticle-based two-photon light-scattering (TPS) assay, for the label-free detection of arsenic and Salmonella bacteria separately, with excellent detection limit and selectivity over other analytes. Our experimental results show that arsenic can be detected quickly and accurately without any tagging, in 100-ppt level with excellent discrimination against other heavy metals. We have demonstrated that our TPS assay is capable of measuring the amount of arsenic in Bangladesh, West Bengal, and Nevada well water as well as in Mississippi river water. We have also shown that gold-nanoparticle-based TPS assay are capable for label-free detection of Salmonella typhimurium (S. typhimurium) with excellent detection limit (103 bacteria/mL) and high selectivity over other pathogens. The mechanism of TPS assay working principle has been discussed. Our results demonstrate the potential for a broad application of nanotechnology in practical defense applications.

Published in:

Nanotechnology, IEEE Transactions on  (Volume:10 ,  Issue: 1 )