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A Solution for Biocompatibility Problems

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4 Author(s)
Scarpa, G. ; Univ. of Rome Tor Vergata, Rome, Italy ; Idzko, A. ; Gotz, S.M. ; Thalhammer, S.

Here, we describe the biocompatibility of solution-processable organic semiconducting polymers. Low-operating voltage organic thin-film transistor (OTFT) devices have been fabricated, which can be used as sensors in electrolytes. The devices are based on regioregular poly(3hexylthiophene) (P3HT), being both a reasonably conductive and optically active polymer. To overcome biocompatibility problems, protein-based coatings and oxygen-plasma treatments have been adopted to enable growth of adherent living cells on those modified surfaces. With the demonstration of biocompatible semiconducting polymeric layers, a hurdle for the realizations of low-cost and mass-produced sensors in life science has been overcome. This opens new possibilities and applications of biological sensing with organic electronic devices.

Published in:

Nanotechnology Magazine, IEEE  (Volume:4 ,  Issue: 3 )

Date of Publication:

Sept. 2010

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