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A 64 Channel Programmable Closed-Loop Neurostimulator With 8 Channel Neural Amplifier and Logarithmic ADC

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4 Author(s)
Jongwoo Lee ; Dept. of Electr. Eng. & Comput. Sci., Univ. of Michigan, Ann Arbor, MI, USA ; Hyo-Gyuem Rhew ; Kipke, D.R. ; Flynn, M.P.

This paper describes a neurostimulation IC for use in advanced closed-loop neurostimulation applications, such as deep brain stimulation (DBS) for treatment and research of neurological disorders including Parkinson's disease. This system senses and filters neural activity with eight pre-amplifiers, a 200 kS/s 8-bit log ADC and digital filters and incorporates 64 programmable current-stimulation channels. The entire device, implemented in 0.18 μm CMOS, occupies 2.7 mm2 and consumes 89 μW in normal operation mode and 271 μW in configuration mode from a 1.8 V supply.

Published in:

Solid-State Circuits, IEEE Journal of  (Volume:45 ,  Issue: 9 )