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In the paper we present the design and test results of an integrated circuit combining the sample&hold and the analogue multiplexer, which is foreseen to be implemented in a multi-channel Application Specific Integrated Circuit (ASIC) for recording signal from alive neuronal tissue. The design is optimised with respect to critical requirements for such circuits, i.e. short sampling time, low power dissipation, good linearity and high dynamic range. Presented design comprises sample&hold circuits with class AB operational amplifier, novel shift register, which allows minimising cross-coupling of the clock signal and control logic. The circuit has been designed in a 0.35 μm CMOS process and has been successfully implemented in a prototype multi-channel ASIC.