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This paper presents frameworks for performing radio resource allocation in Orthogonal Frequency-Division Multiple-Access (OFDMA) networks. The schemes exploit the system interference dynamics to achieve improved system throughput. One of the schemes, the interference-aware is suitable for the conventional (non-relay) network, while the second scheme is conceived for relay-based networks. The two schemes exploit the interference situation. The numerical results show a significant improvement in throughput through the proposed schemes. Our investigation provides insights on the potential performance improvements from a two-hop relaying scheme with simple distributed resource management policies. The results demonstrate that although researchers may be looking for advanced and complex radio resource management (RRM) scheme for future broadband wireless networks, some simple but moderately interferencesmart schemes are enough to provide sufficiently good results.