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A laser based reusable microjet injector for transdermal drug delivery

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2 Author(s)
Han, Tae-hee ; eXtreme Energy Laboratory, School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 151-742, Republic of Korea ; Yoh, Jack J.

Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.3430989 

A laser based needle-free liquid drug injection device has been developed. A laser beam is focused inside the liquid contained in the rubber chamber of microscale. The focused laser beam causes explosive bubble growth, and the sudden volume increase in a sealed chamber drives a microjet of liquid drug through the micronozzle. The exit diameter of a nozzle is 125 μm and the injected microjet reaches an average velocity of 264 m/s. This device adds the time-varying feature of microjet to the current state of liquid injection for drug delivery.

Published in:

Journal of Applied Physics  (Volume:107 ,  Issue: 10 )

Date of Publication:

May 2010

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