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Meta-analysis and Network Analysis of Five Ovarian Cancer Gene Expression Dataset

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6 Author(s)
Hua Dong ; State Key Lab. of Genetic Eng., Fudan Univ., Shanghai, China ; Shengjun Hong ; Xiaomin Xu ; Yanghua Xiao
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Ovarian cancer is the fifth leading cause of death from cancer in women and the leading cause of death from gynecological cancer. Here we present a meta-analysis of five gene expression data sets of 432 ovarian cancer and 42 adjacent normal samples in total. We indentified 3 genes: NDN, RNASE4, IGFBP4 were significantly differentially expressed in both five data sets. After combined the dataset by meta-analysis, 3722 genes were significant (p-value

Published in:

Computational Science and Optimization (CSO), 2010 Third International Joint Conference on  (Volume:1 )

Date of Conference:

28-31 May 2010