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Giant magnetoimpedance-based microchannel system for quick and parallel genotyping of human papilloma virus type 16/18

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13 Author(s)
Yang, Hao ; Institute of Micro/Nano Science and Technology, Shanghai Jiao Tong University, Dong Chuan Road 800, Shanghai 200240, People''s Republic of China ; Chen, Lei ; Lei, Chong ; Zhang, Ju
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Quick and parallel genotyping of human papilloma virus (HPV) type 16/18 is carried out by a specially designed giant magnetoimpedance (GMI) based microchannel system. Micropatterned soft magnetic ribbon exhibiting large GMI ratio serves as the biosensor element. HPV genotyping can be determined by the changes in GMI ratio in corresponding detection region after hybridization. The result shows that this system has great potential in future clinical diagnostics and can be easily extended to other biomedical applications based on molecular recognition.

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Applied Physics Letters  (Volume:97 ,  Issue: 4 )