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In this paper, we study the resource allocation problem in relay aided two-hop uplink multi-user transmission with a single relay node and a single destination node. The orthogonal frequency division multiple access (OFDMA) is adopted as the main transmission modulation. We investigate the problems of subcarrier allocation, subcarrier coupling, and power allocation. The optimization is formulated as maximizing the capacity under constraints of limited number of available subcarriers and a limited amount of power for each source node. A low complexity, suboptimal solution is presented to solve the problem. Simulation results are presented to evaluate the performance of the proposed algorithm.