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Positioning and stretching of actin filaments by electric fields

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4 Author(s)
Wigge, Christoph ; Thin Films and Nanostructures, Bielefeld University, Bielefeld 0521, Germany ; Hinssen, Horst ; Reiss, Gunter ; Herth, Simone

Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.3455338 

The alignment of biological filaments on surfaces offers a high potential for controllable geometries in lab-on-a-chip-structures and micrototal analysis systems. Actin is a polar filamentous protein with a diameter of 7–8 nm that can be manipulated with strong electric fields. It is demonstrated that with the use of microelectrodes or nanoelectrodes and electric fields of 20 kV/m single actin filaments can be manipulated, stretched, and positioned between gold electrodes.

Published in:
Applied Physics Letters  (Volume:96 ,  Issue: 24 )

Date of Publication: Jun 2010

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