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The Python programming language provides a development environment suitable to both computational and visualization tasks. One of Python's key advantages is that it lets developers use packages that extend the language to provide advanced capabilities, such as array and matrix manipulation, image processing, digital signal processing, and visualization. Several popular data exploration and visualization tools have been built in Python, including Visit (www.llnl. gov/visit), Paraview (www.paraview. org), climate data analysis tools (CDAT; www2-pcmdi.llnl.gov/cdat), and VisTrails (www.vistrails .org). In our work, we use VisTrails; however, nearly any Python-enabled application can produce similar results. The neuroscience field often uses bothmultimodal data and computationally complex algorithms to analyze data collected from study participants. Here, we investigate a study in which magnetic resonance imaging (MRI) is combined with electroencephalography (EEG) data to examine working memory.