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This paper reports a novel three-dimensional finite element analysis of coaxial antenna for hepatic microwave ablation. We analyses the temperature distribution pattern and lesion size on hepatic cancer of cap-choke antenna at frequency of 2.45GHz. We set duration time for microwave ablation in the range 60s, 100s, 200s and 300s. We set the potential difference between the inner and an outer conductor was 50V. From our simulation results, if we considered the region where temperature exceeds 50 °C, the threshold for successful hepatic ablation. The temperature distributions that all time had similar characteristics but, there are differently at the lesion size. When we set the ablation time was 300s the lesion size was larger, with a lesion width of approximately 26 mm, compared to 12 mm for set the ablation time was 60s. If we considered the lesion volumes at the ablation time was 300s this case can be induced the highest temperature in cancer tissue and maximum ablation cancer tissue (10.22cm3). In addition, we also set the boundary conditions on temperature control mode which maximum temperature control within hepatic cancer at 96°C, duration time at 300s. From the simulation results, the volume of lesion size was 4.25 cm3, lesion width and depth approximately 18mm, 27mm. respectively.