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Browse Journals & Magazines > Applied Physics Letters ...> Volume:96 Issue:23 Help

On the feasibility of neurocurrent imaging by low-field nuclear magnetic resonance

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10 Author(s)
Burghoff, Martin ; Physikalisch-Technische Bundesanstalt (PTB), Abbestr. 2-12, D-10587 Berlin, Germany ; Albrecht, Hans-Helge ; Hartwig, Stefan ; Hilschenz, Ingo
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Your organization might have access to this article on the publisher's site. To check, click on this link:http://dx.doi.org/+10.1063/1.3441410 

We describe a nuclear magnetic resonance (NMR) spectrometer operating at 20 μT with a frequency resolution of 2 mHz to determine the intrinsic linewidth of the proton resonance in the human brain to be about 3 Hz. Using the same system we measured a biomagnetic field of 0.5 to 1 pT amplitude, which was generated by sustained brain activity evoked during repetitive median nerve stimulation. From these data, the effect of neuronal currents on the proton NMR signal was estimated. We conclude that neuronal currents may cause a measurable shift of the proton NMR line of brain tissue in low-fields.

Published in:
Applied Physics Letters  (Volume:96 ,  Issue: 23 )

Date of Publication: Jun 2010

Page(s):
233701 - 233701-3
ISSN :
0003-6951
Digital Object Identifier :
10.1063/1.3441410
Product Type:
Journals & Magazines
Date of Current Version :
14 June 2010
Issue Date :
Jun 2010

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