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The propagation model of P2P worms can reflect the worm behaviors and identify weakness in the worm propagation which gives guidelines to worm detection and defense. To improve the security of P2P network, a mathematical model is proposed which combines dynamic quarantine and P2P churn. The SIQRW model departs from previous P2P worm models in that considering the dynamic quarantine methods and the peers dynamic join and leave. Using SIQRW model the impact of different parameters on this model is studied. Simulation results show that the performance of our model is significantly better than other models, in terms of decreasing the number of infected hosts and reducing the worm propagation speed.