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The key approach to Hepatitis B treatment are effective evaluation technology for state of patients, personalized treatment, and sequential combination drug adjustment. Based on the characteristics of the treatment for hepatitis B ,this paper analyzed the problems of hospital information systems and traditional medical records, and designed J2EE-based Hepatitis Electronic Medical Records System (HEMR). The HEMR show treatment information of patients and trends in the various test items to physicians intuitively and easily, and assist them to diagnose and research. The system has opened up new ideas and approaches for the diagnosis and treatment of hepatitis B.