By Topic

Valsalva Maneuver for the Analysis of Interaction Hemodynamic Model Study

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

2 Author(s)
Hemalatha, K. ; Appl. Mech., Indian Inst. of Technol. Madras, Chennai, India ; Manivannan, M.

A comprehensive lumped parameter electrical analog model of cardiopulmonary (CP) system to study the interaction between cardiovascular and respiratory system is presented. This model consists of 1) cardiovascular model which integrates four cardiac chambers with valves, pulmonary and systemic circulation, septal and pericardial coupling, and baroreflex control 2) respiratory system with lung mechanics and gas transport at alveolar-capillary membrane. The cardio-pulmonary interaction is realized by intrapleural pressure (Ppl). The governing equations for pressure, volume and flow in each vascular and respiratory compartment are derived from mass balance and continuity principles. Computer simulations are accomplished by numerically integrating the differential equations. Parameters of this combined model are adjusted to fit nominal data, yielding accurate hemodynamic waveforms and validated with literature data. Sensitivity analysis is also performed to individual model parameters. The respiratory influence on aortic pressure is analyzed with pulse pressure (PP) in Valsalva Maneuver(VM). Photoplethesmography is recorded to validate the aortic pressure variations in VM. The maximal percentage changes of PP in phase II of VM shows moderate negative correlation in both simulation and experiment. In summary, this model can be used to analyze cardiopulmonary interactions in normal and pathological states of both the systems.

Published in:

Recent Trends in Information, Telecommunication and Computing (ITC), 2010 International Conference on

Date of Conference:

12-13 March 2010