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Optical tomographic imaging of tumor response to anti-angiogenic drugs in small animals

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10 Author(s)
Flexman, M.L. ; Dept. of Biomed. Eng., Columbia Univ., New York, NY, USA ; Hernandez, S.L. ; Huang, J. ; Johung, T.J.
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Using diffuse optical tomography we have imaged early vascular responses to anti-angiogenic treatments in a small animal tumor model. Images acquired from 1 to 7 days after drug administration show measurable changes in hemoglobin concentration. There are observable differences between mice treated with anti-angiogenic drugs and mice that receive a placebo treatment.

Published in:

Bioengineering Conference, Proceedings of the 2010 IEEE 36th Annual Northeast

Date of Conference:

26-28 March 2010