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There are a lot of people who need health care at home but can't or needn't go to hospital. This paper introduces a solution of home health care telemedicine service system that is composed of remote client system and service center system. The remote client system gathers the vital signs information and transfers it to the service center through 3G/CDMA communication network or Internet. The multi-parameter monitor & transponder can process the signal real-time and send message to the family, guardian when necessary, and it can work independently without the connection with service center. The service center stores and analyzes the data, and medical analysis report will be published in web platform. The system can provide one to one medical expert service, first-aid support service and assistance of personal electronic health documents creation. The system can also be expanded and applied in rural area to improve the medical service situation.