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The paper represents work on the challenge of real time, non-invasive simultaneous acquisition and wireless transmission of human physiological parameters using easy and cost effective approach. Electromyograph (EMG) signal detection and analysis is utilized in various clinical and biomedical applications including generation of control signal for prosthetic tools. However, better solutions to obtain noise free signal using compact detection arrangement and wireless communication technologies are being upgraded. In this work, surface EMG signal is acquired under various levels of bicep muscle contractions using simple computer interface and processed using MATLAB based Filter algorithm for online clean display and wireless transmission. EMG and Carotid artery pulsation are then acquired in time coherence to analyse the effect of rectus abdominis muscle contractions on carotid pulse wave and developed into a stand alone MATLAB executable file. The effect manifests as raised amplitude in the Carotid pulse wave form. Hence, a clear correlation is established between surface EMG signal and Carotid artery pulsation to give a compact, cost efficient solution to physiological signal monitoring.