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Summary form only given. Information Visualization (InfoVis) is a research field dedicated to the design and evaluation of visual representations and interactions to explore and understand large data set. Until recently, the focus of InfoVis has been more on the graphical representation and less on the interaction. However, several new interactive techniques have been published in the past few years, opening perspectives for InfoVis and HCI practitioners. I describe the work conducted at our group, AVIZ, linking traditional HCI interaction research with InfoVis interaction research. I present our latest techniques for navigating large information spaces with varying dimensionalities and topologies. I outline their applicability in HCI problems that are not traditionally viewed as InfoVis in the hope that they will be experimented and adopted in standard interfaces and, more importantly, to emphasize the fact that interaction design for large information spaces is required for our complex specialized applications as well as our everyday working environment.