By Topic

Silica nanoparticles induce apoptosis in human endothelial cells via reactive oxygen species

Sign In

Cookies must be enabled to login.After enabling cookies , please use refresh or reload or ctrl+f5 on the browser for the login options.

Formats Non-Member Member
$31 $13
Learn how you can qualify for the best price for this item!
Become an IEEE Member or Subscribe to
IEEE Xplore for exclusive pricing!
close button

puzzle piece

IEEE membership options for an individual and IEEE Xplore subscriptions for an organization offer the most affordable access to essential journal articles, conference papers, standards, eBooks, and eLearning courses.

Learn more about:

IEEE membership

IEEE Xplore subscriptions

2 Author(s)
Xin Liu ; Shanghai Biomater. Res. & Testing Center, Shanghai Jiaotong Univ., Shanghai, China ; Jiao Sun

To investigate the effect of silica nanoparticles on human endothelial cells, cell viability, apoptosis and the production of reactive oxygen species( ROS) in human umbilical vein endothelial cells (HUVEC) after exposure silica nanoparticles with different concentrations were performed by MTS assay and flow cytometry respectively. Our results showed that silica nanoparticles could cause apoptosis and increase ROS generation in HUVEC in a dose-dependent manner, suggesting that apoptosis in HUVEC could be induced by silica nanoparticles via ROS-dependent pathway.

Published in:

Nanoelectronics Conference (INEC), 2010 3rd International

Date of Conference:

3-8 Jan. 2010