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Highly sensitive and selective label-free detection of cardiac biomarkers in blood serum with silicon nanowire biosensors

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6 Author(s)
Guo-Jun Zhang ; Inst. of Microelectron., A*STAR (Agency for Sci., Technol. & Res.), Singapore, Singapore ; Luo, Z.H.H. ; Min Joon Huang ; Tay, G.K.I.
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Arrays of highly ordered silicon nanowire (SiNW) are fabricated using complementary metal-oxide semiconductor (CMOS) field effect transistor-compatible technology, and the ultrasensitive, label-free, electrical detection of cardiac biomarker in blood serum using the array sensor is demonstrated. The SiNW array biosensor allows for real-time detection of cardiac biomarker in desalted serum, more importantly, multiplexed detection of cardiac biomarkers in untreated and non-desalted blood serum.

Published in:

Electron Devices Meeting (IEDM), 2009 IEEE International

Date of Conference:

7-9 Dec. 2009