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Agile software development methods are widely used globally, especially in building information systems for enterprises. Software developing vendors are suppliers in an informationalization supply chain (ISC) of the customer. To analysis the impact of agile software development on the management of ISC, firstly a brief introduction of agile software development methods is presented. After that the 7 key processes in traditional supply chain management are mapped to processes in ISC management. Then whether agile software development methods could approve these ISC management processes is discussed. Finally, a conclusion is obtained that generally agile software development has positive impact on most of these processes.