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Metallo-dielectric screens have been investigated from the visible to the terahertz spectral region for astronomy and remote sensing applications. These screens are made of periodic structures, which are at resonance with the wavelength of interest. A standing wave of surface wave is formed at resonance conditions, which then enables transmission or reflection of certain bands. Graphene is a monolayer thick 2-D crystal of carbon. Graphene is chemically inert and exhibits very large mobility. Recently, we succeeded in fabricating monolayer and a few layered graphene into films on solid and perforated substrates. By combining the resonance properties of IR screens with the unique properties of graphene, we were able to fabricate a new spectroscopic platform, which enhanced IR and Raman signals of molecules, and specifically, biospecies.