Referenced Items are not available for this document.
In this paper, we describe a circuit-element model for the electric detection of biomolecules in translocation through a nanopore in a semiconductor-oxide-semiconductor (SOS) membrane. The biomolecules are simulated as a superposition of individual charges moving through the nanopore and inducing a charge variation on the membrane electrodes that is modeled as a current source. The SOS membrane is discretized into interconnected elementary circuit elements. The model is tested on the translocation of 11 base single-stranded C3AC7 DNA molecule, for which the electric signal shows good qualitative agreement with the multiscale device approach of Gracheva et al., while quantifying the low-pass filtering in the membrane. Overall, the model confirms the possibility of identifying the sequence of the DNA bases electrically.
Published in:
Nanotechnology, IEEE Transactions on
(Volume:9
,
Issue:
3
)
Date of Publication: May 2010
- Page(s):
- 322 - 329
- ISSN :
- 1536-125X
- INSPEC Accession Number:
- 11304744
- Digital Object Identifier :
- 10.1109/TNANO.2010.2043957
- Product Type:
- Journals & Magazines
- Date of Publication :
- 22 February 2010
- Date of Current Version :
- 13 May 2010
- Issue Date :
- May 2010
- Sponsored by :
- IEEE Nanotechnology Council
About IEEE Xplore | Contact | Help | Terms of Use | Nondiscrimination Policy | Site Map | Privacy & Opting Out of Cookies
A not-for-profit organization, IEEE is the world's largest professional association for the advancement of technology.
© Copyright 2013 IEEE - All rights reserved. Use of this web site signifies your agreement to the terms and conditions.
