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Long term in vitro stability of fully integrated wireless neural interfaces based on Utah slant electrode array

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5 Author(s)
Sharma, Asha ; Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, Utah 84112, USA ; Rieth, Loren ; Tathireddy, P. ; Harrison, R.
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We herein report in vitro functional stability and recording longevity of a fully integrated wireless neural inteace (INI). The INI uses biocompatible Parylene-C as an encapsulation layer, and was immersed in phosphate buffered saline (PBS) for a period of over 150 days. The full functionality (wireless radio-frequency power, command, and signal transmission) and the ability of INI to record artificial action potentials even after 150 days of PBS soaking without any change in signal/noise amplitude constitutes a major milestone in long term stability, and evaluate the encapsulation reliability, functional stability, and potential usefulness for future chronic implants.

Published in:

Applied Physics Letters  (Volume:96 ,  Issue: 7 )

Date of Publication:

Feb 2010

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