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Tumoral and Normal Cells Treatment With High-Voltage Pulsed Cold Atmospheric Plasma Jets

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2 Author(s)
Nicolae Georgescu ; National Institute for Laser, Plasma and Radiation Physics, Bucharest, Romania ; Andreea Roxana Lupu

High-voltage pulsed cold atmospheric plasma jets were used to treat tumoral (B16 and COLO320) and normal (macrophage) cells. Cold atmospheric plasma jet generator and plasma jet physical characteristics are presented. The treatment of the tumoral cells intended to obtain their apoptosis. For tumoral cells, percents of up to 70% apoptosis have been obtained, using helium plasma, activated with up to 2% oxygen. In the same experimental conditions, the plasma treatment did not induce apoptosis in normal (macrophage) cells. In addition, the macrophage cells were not activated by the plasma jets.

Published in:

IEEE Transactions on Plasma Science  (Volume:38 ,  Issue: 8 )