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We report on the use of a radially polarized beam for photothermal therapy of cancer cells labeled with gold nanorods. Due to a three-dimensionally distributed electromagnetic field in the focal volume, the radially polarized beam is proven to be a highly efficient laser mode to excite gold nanorods randomly oriented in cancer cells. As a result, the energy fluence for effective cancer cell damage is reduced to one fifth of that required for a linearly polarized beam, which is only 9.3% of the medical safety level.
Published in:
Applied Physics Letters
(Volume:96
,
Issue:
6
)
Date of Publication: Feb 2010
- Page(s):
- 063702 - 063702-3
- ISSN :
- 0003-6951
- Digital Object Identifier :
- 10.1063/1.3302461
- Product Type:
- Journals & Magazines
- Date of Current Version :
- 17 February 2010
- Issue Date :
- Feb 2010
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