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Motivated by the beauty and the simplicity of biologically inspired algorithm, we study a class of self-organizing protocols based on the pulse-coupled oscillators (PCO). Specifically, we consider two different dynamics of this protocol and show how by flipping the sign of the coupling among the nodes translates into two different emerging pattern: synchrony and de-synchrony. The former is a state where all the nodes pulse at unison. The latter is a situation where the nodes alternate their firings, so that the time between two consecutive firings is constant.