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In this paper, an intelligent real-time patient monitoring system designed to improve the current medical services for the population in the bottom of the pyramid (BOP) has been proposed. The system is composed of three parts: the smart sensor unit, the main processing unit, and the network communication unit. It can gather real-time biosignals; analyze, display, and store these data; be accessed by remote doctor to diagnose on line and upload data stored for further diagnosis through remote computer with the Internet Explorer. The system will be widely used by the general low-income people in the town and country for its advantages of easy use, low cost and satisfying functions.