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A prototype of the MRI-compatible ultra-high resolution SPECT for in vivo mice brain imaging

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3 Author(s)
Jia-Wei Tan ; Department of Nuclear, Plasma and Radiological Engineering, University of Illinois at Urbana-Champaign ; Liang Cai ; Ling-Jian Meng

In this paper, we will present a preliminary study based on a prototype of the MRI-compatible, ultra-high resolution SPECT system for use in a pre-existing Siemens 3.0 T MR scanner. The system uses an ultra-high special resolution energy-resolved photon-counting (ERPC) CdTe detector that we have recently developed. This detector consists of eight detector hybrids, each having a pixilated CdTe detector of 1 mm thickness, bump-bonded to a custom-designed CMOS readout ASIC. Each detector hybrid offers an imaging area of 1.1 cm × 2.2 cm that is divided into an array of 32 × 64 pixels with a pitch size of 350 ¿m × 350 ¿m. A prototype SPECT system has been designed and tailored for use inside the 3.0 T Siemens scanner for tomographic imaging. It consists of a single ERPC detector head, coupled to a collimation aperture. The system is supported by a non-magnetic gantry that allows the system to be moved in and out the Siemens scanner and to be rotated around the object to obtain a sufficient angular sampling. All shielding, supporting and cooling structures are proved to be MRI-compatible. The imaging performance of the prototype system with presence of magnetic field will be evaluated by using image of the Co57 point source and the results will be presented.

Published in:

2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC)

Date of Conference:

Oct. 24 2009-Nov. 1 2009